Soon after it lost its apparent efficacy, we have tried increases (as well as decreases) with Lyrica, with negative results in either direction, so we have always been afraid of getting rid of it completely, continually repeating the mantra 'it is doing something'. Perhaps it is doing something, but what it is doing is merely masking symptoms, not treating them. Her myoclonic seizures have been steadily increasing over the past year, despite increases with Lyrica. After our last neurology visit, we collectively agreed with our neurologist that Mira needed to be taken off of it completely.
Mira has been tapering off it for 4 weeks now, with yesterday being a small 50mg dosage. Early last week, when we dropped from 100mg to 50mg, she had a miserable few days and then seemed to gradually improve by the end of the week. This past week was pretty much a repeat of the week before, so it makes sense that she would be feeling miserable with each decrease. Hopefully, it is all over soon for good.
She has been inconsolable today and cries constantly. Nothing keeps her happy for more than 2-3 minutes. She gets frustrated with her toy, then cries and wails until she is exhausted. She was able to take an hour nap this afternoon, but then proceeded to cry for the next 2 hours. Her appetite is still intact, so there isn't a concern that she is too distraught to eat. We have been giving her Advil periodically, which seems to help some, but there is not much else to do for her but wait it out.